• Article  

      Accurate measurement of microbubble response to ultrasound with a diagnostic ultrasound scanner 

      Keravnou, Christina; Mannaris, Christophoros; AVERKIOU, MICHALAKIS A. (2015)
      Ultrasound and microbubbles are often used to enhance drug delivery and the suggested mechanisms are extravasation and sonoporation. Drug delivery schemes with ultrasound and microbubbles at both low and high acoustic ...
    • Conference Object  

      Adaptive neural network imaging in medical systems 

      Pattichis, Constantinos S.; Pattichis, Marios S. (2001)
      Recent technological advances in medicine facilitated the development of sophisticated equipment enabling the better delivery of health care services. In parallel, artificial neural networks emerged as promising tools for ...
    • Conference Object  

      Atherosclerotic carotid plaque segmentation 

      Loizou, Christos P.; Pattichis, Constantinos S.; Istepanian, Robert Sh Habib; Pantzaris, Marios C.; Nicolaïdes, Andrew N. (2004)
      Atherosclerosis is the major cause of heart attack and stroke in the western world. In this paper we present a computerized method for segmenting the athrerosclerotic carotid plaque from ultrasound images. The method uses ...
    • Article  

      Automatic respiratory gating for perfusion quantification of DCEUS 

      Christofides, Damianos; AVERKIOU, MICHALAKIS A.; Leen, Edward (2013)
      A novel automatic respiratory gating (ARG) algorithm for ultrasound is presented. The ARG algorithm was applied on dual contrast imaging (contrast/tissue) loops in order to remove respiratory motion artifacts from dynamic ...
    • Article  

      Classification of atherosclerotic carotid plaques using morphological analysis on ultrasound images 

      Kyriacou, Efthyvoulos C.; Pattichis, Marios S.; Pattichis, Constantinos S.; Mavrommatis, A.; Christodoulou, Christodoulos I.; Kakkos, Stavros K.; Nicolaïdes, Andrew N. (2009)
      The aim of this study was to investigate the usefulness of multilevel binary and gray scale morphological analysis in the assessment of atherosclerotic carotid plaques. Ultrasound images were recorded from 137 asymptomatic ...
    • Article  

      A comparative study of morphological and other texture features for the characterization of atherosclerotic carotid plaques 

      Christodoulou, Christodoulos I.; Kyriacou, Efthyvoulos C.; Pattichis, Marios S.; Pattichis, Constantinos S.; Nicolaïdes, Andrew N. (2003)
      The extraction of features characterizing the structure of atherosclerotic carotid plaques, obtained by high-resolution ultrasound imaging is important for the correct plaque classification and the estimation of the risk ...
    • Article  

      A Comparison of Ultrasound Intima-Media Thickness Measurements of the Left and Right Common Carotid Artery 

      Loizou, Christos P.; Nicolaïdes, Andrew N.; Kyriacou, Efthyvoulos C.; Georghiou, N.; Griffin, Maura B.; Pattichis, Constantinos S. (2015)
      The intima-media thickness (IMT) of the common carotid artery (CCA) is an established indicator of cardiovascular disease (CVD). There have been reports about the difference between the left and the right sides of the CCA ...
    • Article  

      Completely automated multiresolution edge snapper-A new technique for an accurate carotid ultrasound IMT measurement: Clinical validation and benchmarking on a multi-institutional database 

      Molinari, F.; Pattichis, Constantinos S.; Zeng, G.; Saba, L.; Acharya, U. R.; Sanfilippo, R.; Nicolaïdes, Andrew N.; Suri, J. S. (2012)
      The aim of this paper is to describe a novel and completely automated technique for carotid artery (CA) recognition, far (distal) wall segmentation, and intima-media thickness (IMT) measurement, which is a strong clinical ...
    • Conference Object  

      De-speckle filtering in ultrasound imaging of the carotid artery 

      Christodoulou, Christodoulos I.; Loizou, Christos P.; Pattichis, Constantinos S.; Pantzaris, Marios C.; Kyriacou, Efthyvoulos C.; Pattichis, Marios S.; Schizas, Christos N.; Nicolaïdes, Andrew N. (2002)
      The main objective of this paper is to evaluate the classification performance of de-speckle filtering on ultrasound imaging of the carotid atherosclerotic plaque. The following procedure was investigated on 230 images ...
    • Article  

      The effect of the phase of transmission on contrast agent echoes 

      Morgan, K. E.; AVERKIOU, MICHALAKIS A.; Ferrara, K. (1998)
      Ultrasound contrast agents consist of a gas bubble, encapsulated by a shell for stabilization. The shell dampens the fluctuations in the bubble radius when insonified. The detection of contrast microbubbles during a medical ...
    • Conference Object  

      Global optimization for motion estimation with applications to ultrasound videos of carotid artery plaques 

      Murillo, S.; Pattichis, Marios S.; Soliz, P.; Barriga, S.; Loizou, Christos P.; Pattichis, Constantinos S. (2010)
      Motion estimation from digital video is an ill-posed problem that requires a regularization approach. Regularization introduces a smoothness constraint that can reduce the resolution of the velocity estimates. The problem ...
    • Article  

      Harmonic generation with a dual frequency pulse 

      Keravnou, Christina P.; AVERKIOU, MICHALAKIS A. (2013)
      Nonlinear imaging was utilized in commercial ultrasound systems over the last 15 years offering major advantages in many clinical applications. In this work, pulsing schemes (pulse inversion, power modulated pulse inversion ...
    • Conference Object  

      An integrated system for the assessment of ultrasonic imaging atherosclerotic carotid plaques 

      Pattichis, Constantinos S.; Christodoulou, Christodoulos I.; Pattichis, Marios S.; Pantzaris, Marios C.; Nicolaïdes, Andrew N. (2001)
      The objective of this work is to develop a system that will facilitate the automated characterization of ultrasonic imaging carotid plaques for the identification of individuals with asymptomatic carotid stenosis at risk ...
    • Article  

      An integrated system for the segmentation of atherosclerotic carotid plaque 

      Loizou, Christos P.; Pattichis, Constantinos S.; Pantzaris, Marios C.; Nicolaïdes, Andrew N. (2007)
      In this paper, we propose and evaluate an integrated system for the segmentation of atherosclerotic plaque in ultrasound imaging of the carotid artery based on normalization, speckle reduction filtering, and four different ...
    • Conference Object  

      An integrated teleconsultation system for the evaluation of the risk of stroke 

      Kyriacou, Efthyvoulos C.; Pattichis, Constantinos S.; Christodoulou, Chris C.; Karaolis, Minas A.; Nicolaïdes, Andrew N. (Plymouth University, 2005)
      This paper describes the design and development of an integrated teleconsultation system for the estimation of the annual incidence of stroke related to carotid atherosclerotic plaque and the detection of high risk and low ...
    • Article  

      Investigation of the Relationship of Nonlinear Backscattered Ultrasound Intensity with Microbubble Concentration at Low MI 

      Lampaskis, Marios; AVERKIOU, MICHALAKIS A. (2010)
      Abstract: The aim of this study was to measure the relationship of image intensity with contrast agent concentration. In vitro experiments were performed with a flow phantom and a sulphur hexafluoride filled microbubble ...
    • Article  

      Manual and automated intima-media thickness and diameter measurements of the common carotid artery in patients with renal failure disease 

      Loizou, Christos P.; Kasparis, Takis; Lazarou, Theodoros; Pattichis, Constantinos S.; Pantzaris, Marios C. (2014)
      The objective of this study was to investigate differences in intima-media thickness (IMT) and diameter (D) measurements of the common carotid artery (CCA) in ultrasound imaging in normal subjects and renal failure disease ...
    • Article  

      Manual and automated media and intima thickness measurements of the common carotid artery 

      Loizou, Christos P.; Pattichis, Constantinos S.; Nicolaïdes, Andrew N.; Pantzaris, Marios C. (2009)
      The intima-media thickness (IMT) of the common carotid artery (CCA) is widely used as an early indicator of the development of cardiovascular disease (CVD). It was proposed but not thoroughly investigated that the media ...
    • Conference Object  

      MARTE project: Tele-echography between Kyperounta and Nicosia (Cyprus) 

      Voskarides, Sotos Ch; Avgousti, Sotiris; Kassinopoulos, Marios; Florides, Georgios A.; Pattichis, Constantinos S.; Tziakouri, Chrysa H.; Hadjinicolaou, Marios G.; Capri, A.; Vieyres, Pierre P.; Poisson, G.; Philippe, A.; Smith-Guerin, N.; Fonte, A.; Mourioux, G.; Josserand, L.; Novales, Cyril (2006)
      Ultrasound experts, who are few and not always on hand when needed, have now the tool and the possibility to examine patients from a distance, and thus perform a complete diagnosis without being in the same geographical ...
    • Article  

      Medical imaging fusion applications: An overview 

      Pattichis, Constantinos S.; Pattichis, Marios S.; Micheli-Tzanakou, Litsa Evangelia (2001)
      Computer aided fusion of multi modality medical images provides a very promising diagnostic tool with numerous clinical applications. The objective of this paper is to present an overview of medical imaging fusion techniques ...